Restylane Refyne, Defyne & Kysse*

Are you looking for a filler that keeps your natural expression? This next generation of HA (Hylauonic Acid) dermal filler is Expert Injector logoperfect for you. Using XpresHAn™ (Expression) technology which means it is soft with flexibility, while strong enough to correct agonizing lines and wrinkles other fillers cannot correct. These expression lines of smiling, frowning, smirking, grimacing,puckering up and big wide smiles cheek lines now all can be softened. Patients respond beautifully with these products with a high satisfaction rate. Each product is designed uniquely to correct your specific problem.

*Kysse coming soon

Choose one to learn more about Restylane Refyne, Defyne and Kysse.


Looking for a “natural look” that is not going to change the way you smile and visibly reduce the etched lines made from expressions.

Areas treated with Refyne look natural when smiling and relaxed. The injected area is soft and stretches with expression and draws back when you are in a relaxed resting state. Very high patient satisfaction with minimal bruising. Great for finer lines of the face in areas of the upper and lower lip lines, cheeks, corners of the mouth, chin, smile lines, and the chin.

This product is perfect to just outline your lips without augmentation. Naturally as
you age your lips flatten and roll under. A highly skilled injector can help you
maintain the natural outline of your lips without increasing the size. This product is a
game changer in injectables, generally lasting 12 months. Perfect for the lower face
rejuvenation, where we have spent our whole lives smiling, laughing creating lines
with our expressions.


Why Defyne?

Areas treated with Defyne will gives you little more support for deeper creases still looking natural when you smile and are relaxed. Great for deeper lines of the face in areas on the upper and lower lip, cheeks, chin, marionette lines, smile lines and radial cheek lines.

This product will give you a little more support for those people who are very animated all the time. Defyne will still allow a very natural feeling with no additional fullness to your treated area. It is best for lower face rejuvenation where we have lots of movement.

68 year old woman 1cc Restylane Refyne and 1 cc Restylane Defyne

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Pre- and Post-Treatment Instructions

Pre-Treatment Instructions

7 Days Before Your Treatment (to prevent bruising): AVOID blood thinning over-the-counter medications such as Aspirin, Motrin, Ibuprofen, and Aleve. Also avoid herbal supplements such as Garlic, Vitamin E, Turmeric, Ginko Biloba, St. John’s Wart, and Omega-3 Fish Oil.

3 Days Before Your Treatment: AVOID topical products such as Tretinoin (Retin-A), Retinols, Retinoids, Glycolic Acid, Alpha Hydroxy Acid, or any “Anti-aging” products. Avoid waxing, bleaching, tweezing, or the use of hair removal cream on the area to be treated. 

24 Hours Before Your Treatment: AVOID alcoholic beverages and exercise (to limit risk of bruising).

You must be off any antibiotics for 3 days prior to your appointment. If this is not possible, you need to reschedule your appointment.

Do not use Dermal Fillers if you are pregnant or breastfeeding, are allergic to any of its ingredients, or suffer from any neurological disorders.

Day of Treatment

Notify your provider with any changes to your health history or medications (antibiotics, vitamins, supplement, etc) since your last appointment. This includes new autoimmune conditions, cancer treatments, recent vaccinations, and/or dental procedures. 

If you have previously suffered from cold sores, please inform your injector prior to or during your treatment. There is a chance the needle punctures could contribute to a recurrence. Prescription medication is available that may minimize recurrence of cold sores. 

Please do not wear makeup on the day of treatment on the area being treated.

To maximize your comfort during the procedure a topical anesthetic may be applied (especially when treating the lips), please arrive 30 minutes earlier than your appointment and inform the front desk staff.

During Your Treatment

Dermal Fillers are Hyaluronic Acid products that are injected into the skin to soften creases or folds, support areas of volume loss, or contour specific facial areas. Local numbing medications and ice may be used to maximize your comfort during the procedure. Most patients will have some mild discomfort typically associated with needle injections. 

Tips for Decreasing Bruising

Consume fresh pineapple (contains the enzyme bromelain). Bromelain is a naturally occurring anti-inflammatory that can decrease swelling, tenderness, pain, and bruising.

Start OTC Vitamin C 1, 000 mg supplements 2x/day (AM and PM) 1 week before your appointment. This will help strengthen the walls of your blood vessels. 

Consider starting OTC supplement Arnica the week of your appointment as it has been shown to decrease inflammation and bruising after treatment.

After Your Treatment

You may experience a mild to moderate amount of stinging or soreness post injection. You may also have some redness, swelling, or bruising. This will normally last less than 7 days. 

Some filler may feel firm and bumpy to the touch; it will begin to soften and feel better over the next few weeks. 

Ice should be used immediately after treatment to reduce swelling/bruising. Small bruises sometimes occur and should resolve in 5-10 days. You can also purchase Alastin’s InHance at Aesthetics By Eileen that can shorten the time of bruising. 

You may purchase Jane Iredale Corrective Colors palette to help camouflage all stages of bruising. Oxygenetix is available for purchase at Aesthetics By Eileen and can be used immediately post treatment to conceal signs of treatment. 

Please Avoid After Treatment

Do not rub or massage the treated area for 48 hours after your treatment.

Do not apply makeup or lipstick to the area treated until tomorrow. This will reduce your risk of infection or any other adverse reaction. 

Do not do strenuous exercise for 48 hours post treatment. This will minimize the risk of raising your blood pressure and therefore, reduce the risk of temporary bruising and infection. 

Avoid facials or saunas for 48 hours after your treatment.

Avoid alcohol for the next 48 hours to reduce risk of bruising. 

Do not plan any other facial treatments (Laser, Hydrafacial, Microneedling, etc) for the next 2 weeks.

Treatment Results/Expectations & Follow-Up

If you require more product to touch up/adjust your treatment results, it can be done after the full 14 days (after inflammation has resolved). 

**Please call the office if you experience significant pain, redness, or mottling (uneven reddened or discolored patches on the skin)**

Aesthetics By Eileen Laser & Skin Care Medical Spa 919-881-2100

Text for After Hours Questions 919-999-0233

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